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✦ Odonto Fácilby dra_iswmi
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Histology & EmbryologyIntermediate

Root formation: Hertwig's epithelial root sheath

The root forms thanks to Hertwig's epithelial root sheath: a double layer of epithelium that grows apically (toward where the tip of the root will end up) and defines the shape of the root.
Real histological section of a tooth with its root inside the bone.
A · ToothB · GingivaC · BoneD · Periodontal ligament
Real histological section of a tooth with its root inside the bone.Photo: Dozenist · CC BY-SA 3.0, Wikimedia Commons

What you need to know

  • It appears once the crown has formed. It arises from the cervical loop: the junction of the inner and outer epithelium of the enamel organ.
  • The sheath causes the cells of the papilla to become odontoblasts, which form the dentin of the root.
  • When that first dentin mineralizes, the sheath breaks up. Cells from the follicle come into contact with the dentin and become cementoblasts, which form the cementum.
  • What is left of the sheath stays in the periodontal ligament as the epithelial rests of Malassez.

Terms in plain words

Cervical loopThe rim of the enamel organ where its inner and outer layers meet.
CementoblastCell that forms the cementum covering the root.
Epithelial rests of MalassezClusters of epithelial cells that remain in the periodontal ligament.

For the exam

What remains in the periodontal ligament when Hertwig's root sheath breaks up?

Show answerHide answer

The epithelial rests of Malassez.

Sources

  1. Fate of HERS during Tooth Root Development (research article). View source
  2. Evolution and Development of Hertwig's Epithelial Root Sheath (review). View source

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